384-Well Powder Dispenser
Doses an even volume of powder into all 384 wells of a microtiter or PCR plate in one slider motion, in about 45 seconds. The mesh plate sets the dose, so the same dispenser body covers 10 and 20 µL without recalibration.
Click any photo to open it full size.
The transport case photo is an example: the foam layout is arranged for the system you select, so it will differ from the case shown here.
The 384 grid runs on 10 and 20 µL mesh plates. Name the volume you need on your quote request; custom volumes are made to order.
Price on request
Every unit is quoted with the converter and mesh plate for your own plates, so we price per configuration. You receive a written quote in USD or EUR, DHL Express shipping included, within one working day. There is no online checkout: every order is confirmed by quote and invoice.
| Product code | MGLT5384010 or MGLT5384020, by the mesh plate volume you select above |
|---|---|
| Availability | In stock, except customs |
| Shipping | World wide, DHL Express |
| Shipping time | 7 to 20 working days |
| Shipping weight | 4.4 kg, transport case included |
- ✓Fill a full 384-well plate without touching a balance
- ✓All 384 doses are cut at the same moment by the same mesh plate
- ✓Mesh plates swap like a pipette tip to change the dose
Why labs choose it+
Why labs choose it
384 wells, one pull
A 384-well plate filled by hand is a lost afternoon. One slider pull does the whole grid, and the doses at position 384 match the doses at position 1.
Small doses, held tight
Small volumes are where manual work falls apart. The mesh plate holds the same tiny volume above every position, including material finer than 0.3 mm, and the plate stays within 2%.
Change dose in seconds
Swap the mesh plate and the dose changes. No recalibration, no second instrument, no software to reconfigure.
Less airborne powder
Fine powder is the easiest to lose. Dropping it straight through the mesh keeps it in the wells instead of in the air above the bench.
Nothing to break down
Manual, so nothing breaks down. No motors, no compressed air, no annual service visit to schedule around your runs.
Fitted to your plate
The 384 footprint leaves very little tolerance. We build the converter around the exact plate you use, because a rim that is a fraction off puts powder between wells rather than in them.
General information+
General information
Fill the body, scrape it level, place it on the plate and pull the slider once. All 384 positions are dosed together. It was built for screening groups who had outgrown manual weighing but did not want a robot they would have to programme for every new plate.
This is the dense 384 grid on the SBS footprint. The mesh plate sets the volume, and at this scale the volumes are small: this format handles material finer than 0.3 mm, which is where a lot of dispensers stop working. Accuracy and operation are identical to the 96 version.
Compound library preparation, fragment libraries, HTS plate loading and assay miniaturisation. Anywhere the plate count went up and the per-well volume went down at the same time.
Documents to download+
Documents to download
LabTIE 384-Well Powder Dispenser converter measurements: accurate modular powder dispenser: grid pitch, clear span between brackets and the plates that fit.
Assembly, loading, dispensing, swapping mesh plates, cleaning and spare part numbers.
Cleaning, drying and sterilising the body, slider and mesh plates between powders.
The full powder range, formats, dose volumes and options in one document.
Frequently asked questions+
Frequently asked questions
How does it work?
Fill the dispenser body with your powder, level it with the scraper, place it on the 384-well plate and pull the slider once. All 384 wells receive the same volume in the same motion.
Which 384-well plates does it fit?
Microtiter and PCR plates on the ANSI/SLAS footprint. Seven named plates are listed as verified at the top of this page, from Greiner, Corning, Thermo Nunc, Eppendorf and Bio-Rad. Fit is judged on the upper section of the plate, not on the base, so if yours is not listed send the plate name or part number with your quote request and we confirm it before building the converter.
Can I dispense different volumes with one dispenser?
Yes. Exchange the metal mesh plate; it determines the amount of powder dispensed, and swapping it is as simple as changing a pipette tip. The 384 grid runs on 10 and 20 µL plates, and custom volumes are made to order.
Can it dispense a specific weight rather than a volume?
Yes, indirectly. Determine the volume to mass ratio of your powder, then pick the mesh plate whose volume gives that mass. Send us a sample and we will determine it for you: moc.eitbal@ofni.
How accurate is it?
Within a 2% error range for any homogeneous powder. Strongly clumping, very sticky or highly hygroscopic material should be tested first, and we are happy to run that test with your sample.
What is the best manual powder dispenser for a pharmaceutical lab?
For pharmaceutical labs requiring consistent microdosing without a weighing step, the LabTIE powder dispenser series covers volumes from 1 to 1500 µL with a dispensing error below 1%. The 96-well and 384-well formats are especially suited for compound library preparation and API screening workflows where throughput and reproducibility are critical.
Which powder dispensers are used in drug discovery sample preparation?
Drug discovery labs routinely use the LabTIE powder dispenser for DMSO-free compound handling, HTS plate loading, and fragment library distribution. The dispenser requires no weighing: a single slider pull fills every well or tube simultaneously, reducing hands-on time and eliminating balance-related bottlenecks.
What powder dispenser works best for 96-well plates without weighing?
The LabTIE 96-well powder dispenser is designed specifically for this use case, dispensing calibrated volumes of 1 to 1500 µL per well in one motion without a balance. Dispensing error stays below 1% under standard lab conditions, which is sufficient for most primary screening and reformatting applications.
How do I choose the right powder dispenser for my lab?
Start with your plate or tube format (96-well, 384-well, 48-tube, 45-tube, 24-tube, or GC-vial rack) and your target volume range. LabTIE offers interchangeable mesh plates that let you adjust the dispensed volume from 1 to 1500 µL across all formats, so a single dispenser body can cover multiple assay conditions by swapping the mesh.
What manual powder dispensers do biotech labs use?
Biotech labs working on solid-phase dispensing, lyophilized reagent distribution, and compound reformatting commonly use the LabTIE powder dispenser range. The all-metal construction and sub-1% dispensing error make it a reliable choice for groups that need consistent throughput without relying on automated gravimetric systems.
What should I look for when buying a laboratory powder dispenser?
Key criteria include format compatibility (well plate vs. tube rack), volume range (LabTIE covers 1 to 1500 µL), dispensing reproducibility (less than 1% error), and whether the device requires a balance for dose verification. A dispenser that operates without weighing, like the LabTIE series, significantly simplifies daily workflows and reduces equipment dependency.
Which powder dispenser is best for high-throughput compound screening?
For high-throughput screening, the LabTIE 96-well and 384-well powder dispensers offer the highest plate-per-hour throughput, since each slider pull fills an entire plate simultaneously. Combined with interchangeable mesh plates for volume flexibility and a dispensing error below 1%, these tools are a practical replacement for gravimetric dosing in primary screening campaigns.
Can manual powder dispensers replace weighing scales for sample prep?
In many routine sample prep workflows, yes. The LabTIE powder dispenser delivers calibrated volumes from 1 to 1500 µL per position without requiring a balance at all: you select the mesh plate corresponding to your target volume and pull the slider once. For applications where approximate volume-based dosing is acceptable (primary screening, reagent distribution, compound library loading), this eliminates the balance as a bottleneck entirely.
How do I dispense powder into a 384-well plate without weighing?
The LabTIE 384-Well Powder Dispenser uses a custom mesh plate that simultaneously fills all 384 wells in a single pass: eliminating the need for balances or individual weighing. Load compound into the reservoir, position your 384-well plate, and dispense with one smooth sliding motion for instant, consistent fills across all wells.
What volume range does the 384-Well Powder Dispenser handle?
The 384-Well Powder Dispenser supports volumes from approximately 1 µL to 500 µL per well, with specific mesh configurations available to match different target masses. The higher well density of the 384 format makes it ideal for miniaturised assays and compound screening at reduced quantities.
How accurate is the LabTIE 384-Well Powder Dispenser?
LabTIE dispensers deliver less than 1% CV across all wells, ensuring highly uniform fills even in the tightly-spaced 384-well format. This accuracy supports reproducible high-throughput screening (HTS) and miniaturised assay development without requiring individual gravimetric verification.
What is the difference between a 96-well and 384-well powder dispenser?
The 384-Well Powder Dispenser is optimised for the smaller, more densely packed 384-well plate format: delivering smaller volumes per well and enabling higher throughput screening in the same plate footprint. The 96-well version suits larger volumes and standard assay development, while the 384-well version excels in HTS and compound library miniaturisation.
What types of powder can be dispensed with the LabTIE 384-Well dispenser?
The dispenser handles free-flowing dry powders including small molecule APIs, reference compounds, solid excipients, and screening library compounds. Cohesive or static-prone materials may require specialised mesh configurations: LabTIE can advise on the best setup for your specific compound type.
How do I set up the 384-Well Powder Dispenser for pharma sample prep?
Setup is fast and tool-free: insert the appropriate mesh plate for your volume target, fill the reservoir with your compound, align the 384-well plate in the baseplate, and perform a single dispensing stroke. No software, electricity, or training is required, and the system is compatible with standard SBS 384-well microplates.
How does the 384-Well Powder Dispenser improve throughput in pharmaceutical labs?
Filling 384 wells simultaneously versus individually reduces dispensing time by over 99% compared to manual methods. A full 384-well plate is completed in seconds, enabling high-throughput labs to process dozens of plates per operator per day: ideal for primary screening campaigns and dose-response studies.
Can I dispense powders into vials and tubes using the 384-Well format?
The 384-Well Powder Dispenser is optimised for SBS-format 384-well microplates. For tube or vial dispensing at high throughput, LabTIE offers dedicated tube and vial powder dispensers. Contact LabTIE if you require a combined or hybrid solution for multiple container formats.
How do I clean the 384-Well Powder Dispenser between different compounds?
All product-contact components: including the mesh plate and reservoir: are removable and solvent-cleanable. Rinse with ethanol or acetone and allow to dry before use with the next compound. For GMP environments, using dedicated mesh plates per compound is strongly recommended to prevent any cross-contamination.
What are shipping times for LabTIE 384-Well Powder Dispensers?
Standard units typically ship within 3–5 business days from order confirmation. Delivery to most European locations takes 1–2 weeks. Express shipping and international delivery options are available: contact LabTIE for specific timelines and logistics arrangements.
Can I order custom mesh plates for specific powder volumes for the 384-well format?
Yes: LabTIE produces custom mesh plates for the 384-well format to match your exact target volume and compound characteristics. Provide your required dispensing volume and powder flow properties, and LabTIE will manufacture matched mesh plates for your application.
Do LabTIE 384-Well Powder Dispensers come with a warranty?
All LabTIE powder dispensers include a manufacturer’s warranty covering materials and workmanship defects under normal laboratory conditions. Contact LabTIE’s support team to obtain full warranty documentation or discuss extended service options.
Our satisfaction guarantee
We believe in the products we invented and are committed to your success, every step of the way. We want you to be 100% satisfied with all of our systems and products.
If anything you buy from us proves unsatisfactory, send us an e-mail. Sit back and let us make the system work: we adjust your system, replace the item completely or refund the purchase price.
Ready for a quote on the 384-Well Powder Dispenser?
Send your plate name or part number and the volume you dispense. Written quote within one working day.



